The editor assigned to a manuscript conducts an initial review. Some manuscripts will be rejected at this stage, others may be rejected with the suggestion that the submission be transferred to another journal. Submissions that pass the initial review are sent to external reviewers (mainly through the aurhors published their articles in pubmed to ensure both accuracy and relevance).
Time to first decision is from 8 to 16 days. After that your manuscripts are sent for revision. The maximum period for revision is 45 days.
In most cases you may be asked to resubmit your paper in which case it will be reviewed again to ensure that you have answered their questions and concerns. You should be aware that addressing reviewer's comments does not necessarily ensure publication, and the decision to publish will depend on the overall rating of your submission. When submitting a revised manuscript, please note that you will be asked to submit both a clean manuscript (with the revisions incorporated) and a revised manuscript (with the revisions highlighted).
This journal uses double-blind review, which means that both the reviewer and author identities are concealed from the reviewers, and vice versa, throughout the review process.