E-ISSN 2367-699X | ISSN 2367-7414
 

Original Research 


Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad.

Cited by (1)

Abstract
Objective: To study the relationship between hyperbilirubinemia and acute appendicitis and to evaluate its credibility as a diagnostic marker for acute appendicitis and to evaluate whether elevated serum total bilirubin levels have a predictive potential for the diagnosis of complicated appendicitis
Background: In acute appendicitis occurs through bacterial invasion in appendix leads to transmigration of bacteria and release of TNF-alpha, IL6 and cytokines. These reach the liver through superior mesenteric vein and may produce inflammation or dysfunction of liver either directly or indirectly by altering hepatic blood flow with rising of total serum bilirubin.
Methods: This is a prospective cohort study including Ninety four (94) of adult patients have right iliac fossa pain attending to the Emergency Department (ED) at Suez Canal university Hospital. All 94 patients undergo total serum bilirubin measuring and post-operative histopathological examination of removed appendix.
Results: In this study population of 94 patients and found that thirty-six male patient (38 %) and fifty-eight female patient (62 %), 81 patients (86.2%) were diagnosed as acute appendicitis while 13 patients (13.8%) were normal post-operatively by histopathological reports. Amongst the patients diagnosed with Acute appendicitis post-operatively, 57 patients (70.4%) were found to have elevated serum total bilirubin (>1.2mg/dL) while 24 patients (29.6%) had normal serum total bilirubin levels (≤1.2 mg/dL).
Conclusion: Serum total bilirubin level appears to be a promising new laboratory marker for diagnosing acute appendicitis and have a predictive potential for the diagnosis of complicated appendicitis.

Key words: serum total bilirubin, acute appendicitis


 
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This Article Cited By the following articles

Hyperbilirubinemia as a Predictor of Appendiceal Perforation: A Systematic Review and Diagnostic Test Meta-Analysis
Journal of Clinical Medicine Research 2019; 11(3): 171-178.

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How to Cite this Article
Pubmed Style

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad. Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis. Int J Surg Med. 2017; 3(4): 216-222. doi:10.5455/ijsm.serum-total-bilirubin-as-a-diagnostic-tool-for-acute-appendicitis


Web Style

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad. Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis. http://www.ejos.org/?mno=264399 [Access: November 03, 2020]. doi:10.5455/ijsm.serum-total-bilirubin-as-a-diagnostic-tool-for-acute-appendicitis


AMA (American Medical Association) Style

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad. Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis. Int J Surg Med. 2017; 3(4): 216-222. doi:10.5455/ijsm.serum-total-bilirubin-as-a-diagnostic-tool-for-acute-appendicitis



Vancouver/ICMJE Style

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad. Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis. Int J Surg Med. (2017), [cited November 03, 2020]; 3(4): 216-222. doi:10.5455/ijsm.serum-total-bilirubin-as-a-diagnostic-tool-for-acute-appendicitis



Harvard Style

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad (2017) Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis. Int J Surg Med, 3 (4), 216-222. doi:10.5455/ijsm.serum-total-bilirubin-as-a-diagnostic-tool-for-acute-appendicitis



Turabian Style

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad. 2017. Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis. International Journal of Surgery and Medicine, 3 (4), 216-222. doi:10.5455/ijsm.serum-total-bilirubin-as-a-diagnostic-tool-for-acute-appendicitis



Chicago Style

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad. "Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis." International Journal of Surgery and Medicine 3 (2017), 216-222. doi:10.5455/ijsm.serum-total-bilirubin-as-a-diagnostic-tool-for-acute-appendicitis



MLA (The Modern Language Association) Style

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad. "Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis." International Journal of Surgery and Medicine 3.4 (2017), 216-222. Print. doi:10.5455/ijsm.serum-total-bilirubin-as-a-diagnostic-tool-for-acute-appendicitis



APA (American Psychological Association) Style

Ahmed Elsayed Abouzeid, Mohamed Saleh, Osama Zayed, Mohamed Awad (2017) Validity of Serum Total Bilirubin as a Diagnostic Tool for Acute Appendicitis. International Journal of Surgery and Medicine, 3 (4), 216-222. doi:10.5455/ijsm.serum-total-bilirubin-as-a-diagnostic-tool-for-acute-appendicitis