E-ISSN 2367-699X | ISSN 2367-7414
 

Case Report
Online Published: 31 Jul 2016
 


INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER

Khadija Bellahammou, Asmaa Lakhdissi, Akkar Othman, Salmi Narimane, Ibrahim El Ghissassi, Fadoua Rais, Naoual Benhmidou, Hind M'rabti, Hassan Errihani.


Abstract
Bevacizumab is a recombinant humanized monoclonal antibody targeting the vascular endothelial growth factor; it is actually approved for the treatment of unresectable, locally advanced and metastatic non-small cell lung cancer in association with chemotherapy and as maintenance therapy. Infection risk due to use of bevacizumab is a very rare event. Several cases of aspergillosis in patients treated with monoclonal antibodies have been reported, mostly following treatment with tumor necrosis factor alpha blockers. We present a case of a 60 year-old patient treated for stage IV non-small cell lung cancer, who has been diagnosed with invasive aspergillosis following bevacizumab treatment, and, we postulate that bevacizumab may contribute to this infection.

Key words: Invasive aspergillosis, Bevacizumab


 
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How to Cite this Article
Pubmed Style

Bellahammou K, Lakhdissi A, Othman A, Narimane S, Ghissassi IE, Rais F, Benhmidou N, Mrabti H, Errihani H. INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER. Int J Surg Med. 2016; 2(3): 187-189. doi:10.5455/ijsm.invasive-pulmonary-aspergillosis


Web Style

Bellahammou K, Lakhdissi A, Othman A, Narimane S, Ghissassi IE, Rais F, Benhmidou N, Mrabti H, Errihani H. INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER. https://www.ejos.org/?mno=225447 [Access: June 27, 2026]. doi:10.5455/ijsm.invasive-pulmonary-aspergillosis


AMA (American Medical Association) Style

Bellahammou K, Lakhdissi A, Othman A, Narimane S, Ghissassi IE, Rais F, Benhmidou N, Mrabti H, Errihani H. INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER. Int J Surg Med. 2016; 2(3): 187-189. doi:10.5455/ijsm.invasive-pulmonary-aspergillosis



Vancouver/ICMJE Style

Bellahammou K, Lakhdissi A, Othman A, Narimane S, Ghissassi IE, Rais F, Benhmidou N, Mrabti H, Errihani H. INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER. Int J Surg Med. (2016), [cited June 27, 2026]; 2(3): 187-189. doi:10.5455/ijsm.invasive-pulmonary-aspergillosis



Harvard Style

Bellahammou, K., Lakhdissi, . A., Othman, . A., Narimane, . S., Ghissassi, . I. E., Rais, . F., Benhmidou, . N., Mrabti, . H. & Errihani, . H. (2016) INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER. Int J Surg Med, 2 (3), 187-189. doi:10.5455/ijsm.invasive-pulmonary-aspergillosis



Turabian Style

Bellahammou, Khadija, Asmaa Lakhdissi, Akkar Othman, Salmi Narimane, Ibrahim El Ghissassi, Fadoua Rais, Naoual Benhmidou, Hind Mrabti, and Hassan Errihani. 2016. INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER. International Journal of Surgery and Medicine, 2 (3), 187-189. doi:10.5455/ijsm.invasive-pulmonary-aspergillosis



Chicago Style

Bellahammou, Khadija, Asmaa Lakhdissi, Akkar Othman, Salmi Narimane, Ibrahim El Ghissassi, Fadoua Rais, Naoual Benhmidou, Hind Mrabti, and Hassan Errihani. "INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER." International Journal of Surgery and Medicine 2 (2016), 187-189. doi:10.5455/ijsm.invasive-pulmonary-aspergillosis



MLA (The Modern Language Association) Style

Bellahammou, Khadija, Asmaa Lakhdissi, Akkar Othman, Salmi Narimane, Ibrahim El Ghissassi, Fadoua Rais, Naoual Benhmidou, Hind Mrabti, and Hassan Errihani. "INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER." International Journal of Surgery and Medicine 2.3 (2016), 187-189. Print. doi:10.5455/ijsm.invasive-pulmonary-aspergillosis



APA (American Psychological Association) Style

Bellahammou, K., Lakhdissi, . A., Othman, . A., Narimane, . S., Ghissassi, . I. E., Rais, . F., Benhmidou, . N., Mrabti, . H. & Errihani, . H. (2016) INVASIVE PULMONARY ASPERGILLOSIS FOLLOWING BEVACIZUMAB TREATMENT FOR NON-SMALL CELL LUNG CANCER. International Journal of Surgery and Medicine, 2 (3), 187-189. doi:10.5455/ijsm.invasive-pulmonary-aspergillosis