E-ISSN 2367-699X | ISSN 2367-7414
 
2023, Vol: 9, Issue: 5
9 / 5Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Copyright Transfer Form

Original Research
Online Published: 31 Jul 2016
 


CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov.


Abstract
Objective: The objective of this study is to determine the change in IL-6 serum levels in patients undergoing preemptive analgesia and surgical removal of an impacted mandibular third molar.
Study Design: This is a prospective, double-blind, placebo-controlled study in 80 patients who had an atypical extraction of an impacted mandibular third molar.
Results: After surgical removal of impacted mandibular third molars, elevated levels of IL-6 in the early postoperative period were found, and the highest level was 14 pg/ml.
Conclusion: Postoperative IL-6 levels rise regardless of the medication used for preemptive analgesia. In the group treated with nimesulide, a trend to reducing IL-6 levels was observed, but further study in a larger number of patients is needed.

Key words: interleukin-6, preemptive analgesia, third molar surgery


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Deyan Zdravkov Neychev
Articles by Irina Stanimirova
Articles by Kiril Kostov Simitchiev
Articles by Mariana Murdjeva
Articles by Dimitar Atanasov
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov. CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS. Int J Surg Med. 2016; 2(3): 111-116. doi:10.5455/ijsm.mandibular-third-molar

Web Style

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov. CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS. https://www.ejos.org/?mno=225611 [Access: September 12, 2024]. doi:10.5455/ijsm.mandibular-third-molar

AMA (American Medical Association) Style

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov. CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS. Int J Surg Med. 2016; 2(3): 111-116. doi:10.5455/ijsm.mandibular-third-molar


Vancouver/ICMJE Style

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov. CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS. Int J Surg Med. (2016), [cited September 12, 2024]; 2(3): 111-116. doi:10.5455/ijsm.mandibular-third-molar


Harvard Style

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov (2016) CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS. Int J Surg Med, 2 (3), 111-116. doi:10.5455/ijsm.mandibular-third-molar


Turabian Style

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov. 2016. CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS. International Journal of Surgery and Medicine, 2 (3), 111-116. doi:10.5455/ijsm.mandibular-third-molar


Chicago Style

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov. "CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS." International Journal of Surgery and Medicine 2 (2016), 111-116. doi:10.5455/ijsm.mandibular-third-molar


MLA (The Modern Language Association) Style

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov. "CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS." International Journal of Surgery and Medicine 2.3 (2016), 111-116. Print. doi:10.5455/ijsm.mandibular-third-molar


APA (American Psychological Association) Style

Deyan Zdravkov Neychev, Irina Stanimirova, Kiril Kostov Simitchiev, Mariana Murdjeva, Dimitar Atanasov (2016) CHANGES IN SERUM LEVELS OF IL-6 IN THE EARLY POSTOPERATIVE PERIOD AFTER PREEMPTIVE ANALGESIA WITH NIMESULIDE, METAMIZOLE SODIUM AND PLACEBO IN REMOVAL OF IMPACTED MANDIBULAR THIRD MOLARS. International Journal of Surgery and Medicine, 2 (3), 111-116. doi:10.5455/ijsm.mandibular-third-molar


Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessAuthor's Rights and ObligationsPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information

About International Journal of Surgery and Medicine

International Journal of Surgery and Medicine E-ISSN: 2367-699X | P-ISSN: 2367-7414 International Journal of Surgery and Medicine (IJSM) is an inter ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information


 

Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the International Journal of Surgery and Medicine editorial office as follows:

Bulgarian Association of Young Surgeons (BAYS)

inkov@journalmedica.com

Financial department is managed by International Sci Ink Press. 

It is a company registered in Bulgaria with registered no. 205414288 and registered address at 57 Antim I str., Vazrazhdane, Sofia, 1303, Bulgaria.

Tel: +359883427500